Background:

CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Alternative names:

B7DC, CD273, PDCD1L2, PDL2

Description:

Antibody for flow cytometry

Species reactivity:

Human

Host:

Mouse

Isotype:

Mouse IgG2a, κ

Concentration:

Request info at info@sobekbio.com

Buffer:

PBS with 0.05% Proclin300, 1% BSA

Conjugation:

PE

Applications:

FCM

Storage:

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com