Background:

CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Alternative names:

Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5

Description:

Antibody for flow cytometry

Species reactivity:

Mouse

Host:

Rat

Isotype:

Rat IgG2a, κ

Concentration:

0.5 mg/mL

Buffer:

0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Conjugation:

None (Purified antibody-Azide Free/Low endotoxin)

Applications:

FCM

Storage:

Store at 2~8°C. Do not freeze.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com