Background:

CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Alternative names:

Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP

Description:

Antibody for flow cytometry

Species reactivity:

Human,Mouse,Rat

Host:

Mouse

Isotype:

Mouse IgG1, κ

Concentration:

0.5 mg/mL

Buffer:

0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Conjugation:

None (Purified antibody-Azide Free/Low endotoxin)

Applications:

FCM

Storage:

Store at 2~8°C. Do not freeze.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com