Alternative names:

FGQTL2, MEL-1B-R, MT2

Description:

Human MTR1B full length protein-synthetic nanodisc

Background:

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]

Protein families:

Transmembrane,Druggable Genome,

Protein pathways:

GPCRDB Class A Rhodopsin-like,Small ligand GPCRs,Cancer,

Expression host:

HEK293

Target:

MTR1B

Molecular weight:

The human full length MTR1B protein has a MW of 40.2kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com