Alternative names:

BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7

Description:

Human LT4R1 full length protein-synthetic nanodisc

Background:

Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.[UniProtKB/Swiss-Prot Function]

Protein families:

GPCR,Transmembrane,Druggable Genome,

Protein pathways:

GPCRDB Class A Rhodopsin-like,Nucleotide GPCRs,Cancer,Chemokines,Asthma,Autoimmune & Inflammatory Response,Chemokine and Receptor,

Expression host:

HEK293

Target:

LT4R1

Molecular weight:

The human full length LT4R1 protein has a MW of 37.6kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com