Alternative names:

HHG, LCGR, LGR2, LH/CG-R, LH/CGR, LHR, LHRHR, LSH-R, ULG5

Description:

Human LSHR full length protein-synthetic nanodisc

Background:

This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]

Protein families:

Transmembrane,Druggable Genome,

Protein pathways:

GPCRDB Class A Rhodopsin-like,Ovarian Infertility Genes,Peptide GPCRs,Cancer,G-Protein Coupled Receptors Signaling Pathway,

Expression host:

HEK293

Target:

LSHR

Molecular weight:

The human full length LSHR protein has a MW of 78.6kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com