Alternative names:

BETA3AR

Description:

Human ADRB3 full length protein-synthetic nanodisc

Background:

The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]

Protein families:

GPCR,Transmembrane,Druggable Genome,

Protein pathways:

Calcium regulation in cardiac cells,GPCRDB Class A Rhodopsin-like,Monoamine GPCRs,Cancer,Metabolic and Obesity,Insulin Signaling Pathway ,

Expression host:

HEK293

Target:

ADRB3

Molecular weight:

The human full length ADRB3 protein has a MW of 43.5kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com