Alternative names:

ADRA1C, ADRA1L1, ALPHA1AAR

Description:

Human ADA1A full length protein-synthetic nanodisc

Background:

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]

Protein families:

GPCR,Transmembrane,Druggable Genome,

Protein pathways:

Calcium regulation in cardiac cells,GPCRDB Class A Rhodopsin-like,Monoamine GPCRs,Apoptosis,Cancer,Cell Cycle,

Expression host:

HEK293

Target:

ADA1A

Molecular weight:

The human full length ADA1A protein has a MW of 51.5kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com