Alternative names:

BMIQ20

Description:

Human MC4R full length protein-synthetic nanodisc

Background:

The protein is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.

Protein families:

Druggable Genome, GPCR, Transmembrane

Protein pathways:

Neuroactive ligand-receptor interaction

Expression host:

HEK293

Target:

MC4R

Molecular weight:

The human full length MC4R protein has a MW of 36.9 kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com