Alternative names:

CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4

Description:

Human CCR4 full length protein-synthetic nanodisc

Background:

The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Protein families:

GPCR

Protein pathways:

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Expression host:

HEK293

Target:

CCR4

Molecular weight:

The human full length CCR4 Protein has a MW of 41.4 kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com