Alternative names:

HPT-1;HPT-1/LI

Description:

Recombinant mouse CDH17 protein with C-terminal 6×His tag

Background:

Enables proton-dependent oligopeptide secondary active transmembrane transporter activity. Involved in germinal center B cell differentiation; marginal zone B cell differentiation; and spleen development. Acts upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and oligopeptide transport. Located in cell surface and plasma membrane. Is expressed in several structures, including common bile duct; gut; spleen; trunk; and urogenital sinus. Orthologous to human CDH17 (cadherin 17). [provided by Alliance of Genome Resources, Apr 2022]

Molecular characterization:

Mouse CDH17(Phe26-Met786) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 85.1 kDa after removal of the signal peptide. The apparent molecular mass of mCDH17-His is approximately 70-130 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

CDH17

Purity:

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com