Alternative names:

CAR;MCAR;MCVADR

Description:

Recombinant mouse CXADR protein with C-terminal 6×His tag

Background:

This gene encodes a protein that is part of the Cortical Thymocyte marker in Xenopus (CTX) subfamily within the immunoglobulin superfamily. Members of this subfamily, predominantly expressed on the surface of endothelial and epithelial cells, help establish cell polarity and provide a barrier function, regulating migration of immune cells. This protein, first identified as the receptor for adenovirus subgroup C and coxsakieviruses group B, is developmentally regulated and plays an important role in cardiac development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]

Molecular characterization:

Mouse CXADR(Leu20-Gly237) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 24.9 kDa after removal of the signal peptide. The apparent molecular mass of mCXADR-His is approximately 15-35 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

CXADR

Purity:

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com