Alternative names:

CDHF5;HDGC

Description:

Recombinant Human DSG2(24-609) Protein with C-terminal 6×His tag

Background:

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]

Molecular characterization:

DSG2(Leu24-Gly609) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 66.4 kDa after removal of the signal peptide. The apparent molecular mass of DSG2(24-609)-His is approximately 70-100 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

DSG2

Purity:

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com