Alternative names:

AngX;CDT6;dJ647M16.1

Description:

Recombinant Human ANGPTL7 Protein with C-terminal 6×His tag

Background:

Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193). Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036).[UniProtKB/Swiss-Prot Function]

Molecular characterization:

ANGPTL7(Gln27-Pro346) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 37.9 kDa after removal of the signal peptide. The apparent molecular mass of ANGPTL7-His is approximately 35-55 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

ANGPTL7

Purity:

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

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