Alternative names:

CLEC2;CLEC2B;PRO1384;QDED721

Description:

Recombinant Human CLEC1B Protein with N-terminal 6×His tag

Background:

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]

Molecular characterization:

6×His tag CLEC1B(Ser55-Pro229)

Molecular weight:

The protein has a predicted molecular mass of 21.5 kDa after removal of the signal peptide. The apparent molecular mass of His-CLEC1B is approximately 25-35 kDa due to glycosylation.

Tag:

N-6×His Tag

Expression host:

HEK293

Target:

CLEC1B

Purity:

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com