Alternative names:

CAD11;CDHOB;ESWS;OB;OSF-4

Description:

Recombinant Human CDH11(23-617) Protein with C-terminal 6×His tag

Background:

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]

Molecular characterization:

CDH11(23-617)(Phe23-Thr617) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 66.4 kDa after removal of the signal peptide. The apparent molecular mass of CDH11(23-617)-His is approximately 70-100 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

CDH11

Purity:

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com