Human IFN alpha4 (C-6His) Protein PME30050
Alternative names:
Interferon alpha-4;Interferon alpha-4B;Interferon alpha-76;Interferon alpha-M1;IFNA4
Description:
Recombinant Human Interferon Alpha-4 is produced by our Mammalian expression system and the target gene encoding Cys24-Asp189 is expressed with a 6His tag at the C-terminus.
Background:
Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410.
Molecular characterization:
Not available
Molecular weight:
20.4 KDa
Tag:
C-6×His Tag
Expression host:
HEK293
Target:
IFN
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Formulation / Reconstitution:
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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