Alternative names:

Insulin-Like Growth Factor I;IGF-I;Mechano Growth Factor;MGF;Somatomedin-C;IGF1;IBP1

Description:

Recombinant Human Insulin-like Growth Factor I(4-70) is produced by our E.coli expression system and the target gene encoding Thr52-Ala118 is expressed.

Background:

Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.

Molecular characterization:

Not available

Molecular weight:

7.3 KDa

Tag:

Expression host:

E.coli

Target:

IGF-I

Purity:

Greater than 95% as determined by reducing SDS-PAGE.

Formulation / Reconstitution:

Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com