Alternative names:

VCAM1;INCAM-100

Description:

Recombinant human CD106 Protein with C-terminal Human Fc tag

Background:

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

Molecular characterization:

CD106(Phe25-Glu698) hFc(Glu99-Ala330)

Molecular weight:

The protein has a predicted molecular mass of 100.4 kDa after removal of the signal peptide. The apparent molecular mass of CD106-hFc is approximately 100-130 kDa due to glycosylation.

Tag:

C-Human Fc Tag

Expression host:

HEK293

Target:

CD106

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com