Alternative names:

CC-CKR-4;CD194;ChemR13;CKR4;CMKBR4;HGCN:14099;K5-5

Description:

Recombinant human CCR4(1-39) protein with C-terminal mouse Fc tag

Background:

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]

Molecular characterization:

CCR4(1-39)(Met1-Glu39) mFc(Pro99-Lys330)

Molecular weight:

The protein has a predicted molecular mass of 30.7 kDa after removal of the signal peptide. The apparent molecular mass of CCR4(1-39)-mFc is approximately 35-55 kDa due to glycosylation.

Tag:

C-Mouse Fc Tag

Expression host:

HEK293

Target:

CCR4

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com