Alternative names:

TIMP-4

Description:

Recombinant human TIMP4 protein with C-terminal human Fc tag

Background:

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008]

Molecular characterization:

TIMP4(Cys30-Pro224) hFc(Glu99-Ala330)

Molecular weight:

The protein has a predicted molecular mass of 48.6 kDa after removal of the signal peptide. The apparent molecular mass of TIMP4-hFc is approximately 55-70 kDa due to glycosylation.

Tag:

C-Human Fc Tag

Expression host:

HEK293

Target:

TIMP4

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com