Alternative names:

Atypical chemokine receptor 3;XC-R7;XCR-7;hemokine orphan receptor 1;-protein coupled receptor 159;DC-1

Description:

Recombinant human CXCR7 protein with C-terminal human Fc tag

Background:

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]

Molecular characterization:

CXCR7(Met1-Lys40) hFc(Glu99-Ala330)

Molecular weight:

The protein has a predicted molecular mass of 31.0 kDa after removal of the signal peptide. The apparent molecular mass of CXCR7-hFc is approximately 35-55 kDa due to glycosylation.

Tag:

C-Human Fc Tag

Expression host:

HEK293

Target:

CXCR7

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

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