Alternative names:

NBC2;NBC3;NBCN1;SBC2;SLC4A6

Description:

Recombinant human SLC4A7 protein with C-terminal 6×His tag

Background:

This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]

Molecular characterization:

SLC4A7(Met1-Cys608) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 68.6 kDa after removal of the signal peptide. The apparent molecular mass of SLC4A7-His is approximately 100-130 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

SLC4A7

Purity:

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com