Alternative names:

ANG-5;ANGPT5;ANL3;FHBL2

Description:

Recombinant human ANGPTL3 protein with C-terminal 6×His tag

Background:

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.

Molecular characterization:

ANGPTL3(Ser17-Arg221) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 24.8 kDa after removal of the signal peptide.The apparent molecular mass of ANGPTL3-His is approximately 25-35 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

ANGPTL3

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

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