Alternative names:

CD132;CIDX;IL-2RG;IMD4;P64;SCIDX;SCIDX1

Description:

Recombinant human IL2RG protein with C-terminal human Fc tag

Background:

The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]

Molecular characterization:

IL2RG(Leu23-Asn254) hFc(Glu99-Ala330)

Molecular weight:

The protein has a predicted molecular mass of 53.5 kDa after removal of the signal peptide. The apparent molecular mass of IL2RG-hFc is approximately 70-100 kDa due to glycosylation.

Tag:

C-Human Fc Tag

Expression host:

HEK293

Target:

IL2RG

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com