Alternative names:

HFREP1;HP-041;HPS;LFIRE-1;LFIRE1

Description:

Recombinant Human FGL1 Protein with N-terminal human Fc tag

Background:

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]

Molecular characterization:

hFc(Glu99-Ala330) FGL1(Leu23-Ile312)

Molecular weight:

The protein has a predicted molecular mass of 60.1 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FGL1 is approximately 55-70 kDa due to glycosylation.

Tag:

N-Human Fc Tag

Expression host:

HEK293

Target:

FGL1

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com