Alternative names:

CD127;CDW127;IL-7R-alpha;IL7RA;ILRA

Description:

Recombinant Human IL7RA with C-terminal human Fc tag

Background:

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]

Molecular characterization:

IL7RA(Glu21-Gly236) hFc(Glu99-Ala330)

Molecular weight:

The protein has a predicted molecular mass of 51.0 kDa after removal of the signal peptide.The apparent molecular mass of IL7RA-hFc is approximately 55-100 kDa due to glycosylation.

Tag:

C-Human Fc Tag

Expression host:

HEK293

Target:

IL7RA

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com