Alternative names:

CD244;2B4;SLAMF4;NKR2B4;NAIL;h2B4

Description:

Recombinant human 2B4 protein with C-terminal human Fc tag

Background:

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular characterization:

2B4(Cys22-Ala221) hFc(Glu99-Ala330)

Molecular weight:

The protein has a predicted molecular mass of 47.7 kDa after removal of the signal peptide.

Tag:

C-Human Fc Tag

Expression host:

HEK293

Target:

2B4

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com