Alternative names:

DNAM1;CD226;PTA1

Description:

Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6×His tag

Background:

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

Molecular characterization:

DNAM-1(Glu19-Asn247) mFc(Pro99-Lys330) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 53.5 kDa after removal of the signal peptide.

Tag:

C-Mouse Fc and 6×His Tag

Expression host:

HEK293

Target:

DNAM-1

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com