Alternative names:

ALXDRD

Description:

Recombinant human GFAP(68-377) protein with N-terminal 6×His tag

Background:

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Molecular characterization:

6×His tag GFAP(Ser68-Ile377)

Molecular weight:

The protein has a predicted molecular mass of 37.2 kDa after removal of the signal peptide. The apparent molecular mass of His-GFAP(68-377) is approximately 35-55 kDa due to glycosylation.

Tag:

N-6×His Tag

Expression host:

HEK293

Target:

GFAP

Purity:

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com