Alternative Name(s):

H2-D1; H-2 class I histocompatibility antigen; D-D alpha chain; H-2D(D)

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

H2-D1

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

GSHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGCDVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAGAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPLGKEQKYTCHVEHEGLPEPLTLRWGKEEPPSSTKTNT

Expression Region:

25-311aa

Subcellular Location:

Membrane, Single-pass type I membrane protein

Tissue Specificity:

Protein Length:

Extracellular Domain

Pathway:

Mol. Weight:

35.2 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Involved in the presentation of foreign antigens to the immune system.

Involvement in disease:

Relevance:

Involved in the presentation of foreign antigens to the immune system.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

MHC class I family

Reference:

"The B144-H-2Db interval and the location of a mouse homologue of the human D6S81E locus."Wroblewski J.M., Kaminsky S.G., Milisauskas V.K., Pittman A.M., Chaplin D.D., Spies T., Nakamura I.Immunogenetics 32:200-204(1990)