Alternative Name(s):

(Growth hormone secretagogue)(Growth hormone-releasing peptide)(Motilin-related peptide)

Species: (Organism)

Canis lupus familiaris (Dog) (Canis familiaris)

Gene Names:

GHRL

Tag info:

N-terminal GST-tagged

Target Protein AA Sequence:

GSSFLSPEHQKLQQRKESKKPPAKLQPR

Expression Region:

24-51aa

Subcellular Location:

Tissue Specificity:

Protein Length:

Partial

Pathway:

Mol. Weight:

29.9 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Involvement in disease:

Relevance:

[Ghrelin]: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; [Obestatin]: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"A role of ghrelin in canine mammary carcinoma cells proliferation, apoptosis and migration." Majchrzak K., Pawlowski K.M., Orzechowska E.J., Dolka I., Mucha J., Motyl T., Krol M. BMC Vet Res 8:170-170(2012)