Alternative Name(s):

(Lysosomal acid GCase)(Acid beta-glucosidase)(Beta-glucocerebrosidase)(Cholesterol glucosyltransferase)(SGTase)(Cholesteryl-beta-glucosidase)(D-glucosyl-N-acylsphingosine glucohydrolase)(Lysosomal cholesterol glycosyltransferase)(Lysosomal galactosylceramidase)(Lysosomal glycosylceramidase)

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

Gba

Tag info:

Tag-Free

Target Protein AA Sequence:

AQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYESTRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLIHQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSSHDVKLLMLDDQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPIIVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ

Expression Region:

20-515aa

Subcellular Location:

Tissue Specificity:

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

55.6 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Metabolism

Function:

Involvement in disease:

Relevance:

Acid beta-glucosidase Beta-glucocerebrosidase D-glucosyl-N-acylsphingosine glucohydrolase

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"Comparison of the chromosomal localization of murine and human glucocerebrosidase genes and of the deduced amino acid sequences." O'Neill R.R., Tokoru T., Kozak C.A., Brady R.O. Proc. Natl. Acad. Sci. U.S.A. 86:5049-5053(1989)