Alternative Name(s):

Parotid secretory protein

Species: (Organism)

Homo sapiens (Human)

Gene Names:

BPIFA2

Tag info:

N-terminal 6xHis-sumostar-tagged

Target Protein AA Sequence:

ESLLDNLGNDLSNVVDKLEPVLHEGLETVDNTLKGILEKLKVDLGVLQKSSAWQLAKQKAQEAEKLLNNVISKLLPTNTDIFGLKISNSLILDVKAEPIDDGKGLNLSFPVTANVTVAGPIIGQIINLKASLDLLTAVTIETDPQTHQPVAVLGECASDPTSISLSLLDKHSQIINKFVNSVINTLKSTVSSLLQKEICPLIRIFIHSLDVNVIQQVVDNPQHKTQLQTLI

Expression Region:

19-249aa

Subcellular Location:

Secreted

Tissue Specificity:

Detected in submandibular gland. Secreted into saliva.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

41.1 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Developmental Biology

Function:

Has strong antibacterial activity against P. aeruginosa.

Involvement in disease:

Relevance:

Has strong antibacterial activity against P. aeruginosa.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

BPI/LBP/Plunc superfamily, Plunc family

Reference:

"Human parotid secretory protein is a lipopolysaccharide-binding protein: identification of an anti-inflammatory peptide domain." Abdolhosseini M., Sotsky J.B., Shelar A.P., Joyce P.B., Gorr S.U. Mol. Cell. Biochem. 359:1-8(2012)