Alternative Name(s):

Dander allergen Equ c 4/Equ c 5

Species: (Organism)

Equus caballus (Horse)

Gene Names:

LATH

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

QQIPPEVSSQITDALTQGLLDGNFLSLLNAINLEGLLNTILDQVTGLLNILVGPLLGPSDAEIKLQDTRLLQLSLEFSPDSKGIDIWIPLELSVYLKLLILEPLTLYVRTDIRVQLRLESDEDGKYRLAFGHCSLLPRAIELQSGNPLSLPVNAVLGTIENALGNFITEDLGAGLCPTLNSLVSNLDLQLVNNLINLILDRANVDLSV

Expression Region:

21-228aa

Subcellular Location:

Secreted

Tissue Specificity:

Found in sweat (at protein level).

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

24.6 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Major protein in sweat, has surfactant properties. Has a role in temperature regulation by having a capacity to make hydrophobic surfaces wettable and so can function in promoting spreading and evaporation of sweat.

Involvement in disease:

Relevance:

Major protein in sweat, has surfactant properties. Has a role in temperature regulation by having a capacity to make hydrophobic surfaces wettable and so can function in promoting spreading and evaporation of sweat.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

BPI/LBP/Plunc superfamily, Plunc family

Reference:

"Biochemical characterization and surfactant properties of horse allergens."Goubran Botros H., Poncet P., Rabillon J., Fontaine T., Laval J.-M., David B.Eur. J. Biochem. 268:3126-3136(2001)