Alternative Name(s):

Cell surface glycoprotein A15Membrane component chromosome X surface marker 1T-cell acute lymphoblastic leukemia-associated antigen 1 ;TALLA-1Transmembrane 4 superfamily member 2;; CD231

Species: (Organism)

Homo sapiens (Human)

Gene Names:

TSPAN7

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

RHEIKDTFLRTYTDTMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNM

Expression Region:

113-213aa

Subcellular Location:

Membrane, Multi-pass membrane protein

Tissue Specificity:

Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients.

Protein Length:

Partial

Pathway:

Mol. Weight:

14.5 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Immunology

Function:

May be involved in cell proliferation and cell motility.

Involvement in disease:

Mental retardation, X-linked 58 (MRX58)

Relevance:

May be involved in cell proliferation and cell motility.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Tetraspanin (TM4SF) family

Reference:

Isolation of a novel cDNA clone showing marked similarity to ME491/CD63 superfamily.Emi N., Kitaori K., Seto M., Ueda R., Saito H., Takahashi T.Immunogenetics 37:193-198(1993)