Alternative Name(s):

GLTPGlycolipid transfer protein; GLTP

Species: (Organism)

Bos taurus (Bovine)

Gene Names:

GLTP

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

ALLAEHLLRPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPTKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKVRLFLVNYTATIDVIYEMYTRMNAELNYKV

Expression Region:

2-209aa

Subcellular Location:

Cytoplasm

Tissue Specificity:

Detected in brain, kidney, spleen, lung, cerebellum, liver and heart.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

25.8 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Signal Transduction

Function:

Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.

Involvement in disease:

Relevance:

Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

GLTP family

Reference:

"Structural evidence for adaptive ligand binding of glycolipid transfer protein." Airenne T.T., Kidron H., Nymalm Y., Nylund M., West G., Mattjus P., Salminen T.A. J. Mol. Biol. 355:224-236(2006)