Alternative Name(s):

Carcinoembryonic antigen CGM7Non-specific cross-reacting antigen W236

Species: (Organism)

Homo sapiens (Human)

Gene Names:

CEACAM4

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

FTIEALPSSAAEGKDVLLLACNISETIQAYYWHKGKTAEGSPLIAGYITDIQANIPGAAYSGRETVYPNGSLLFQNITLEDAGSYTLRTINASYDSDQATGQLHVHQNNVPGLPVGAVAG

Expression Region:

36-155aa

Subcellular Location:

Membrane, Single-pass type I membrane protein

Tissue Specificity:

Granulocytes.

Protein Length:

Partial

Pathway:

Mol. Weight:

14.7 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Immunology

Function:

Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.

Involvement in disease:

Relevance:

Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Immunoglobulin superfamily, CEA family

Reference:

Molecular cloning of nonspecific cross-reacting antigens in human granulocytes.Kuroki M., Arakawa F., Matsuo Y., Oikawa S., Misumi Y., Nakazato H., Matsuoka Y.J. Biol. Chem. 266:11810-11817(1991)