Alternative Name(s):

Placental cadherin

Species: (Organism)

Sus scrofa (Pig)

Gene Names:

CDH3

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

KIAKYELFGHAVSENGASVEEPMNISIIVTDQNDHKPKFTQDVFRGSVLEGVLPGTSVMQVTATDEDDAINTYNGVVAYSILSQEPKDPHDLMFTVHRSTGAISVISSGLDRERVPEYTLTIQATDMDGDGSSTTATAIVEILDA

Expression Region:

1-145aa

Subcellular Location:

Cell membrane, Single-pass type I membrane protein

Tissue Specificity:

Protein Length:

Full Length

Pathway:

Mol. Weight:

17.6 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Signal Transduction

Function:

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Involvement in disease:

Relevance:

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"Expression of multiple cadherins in adult retinal pigment epithelial (RPE) cells." Lutz D.A., Zheng J.J. Submitted (NOV-1997)