Alternative Name(s):

MGC125477; MGC125478; MGC125479; MGC125480; Neurexophilin 2; Neurexophilin-2; NPH2; Nxph2; NXPH2_HUMAN

Species: (Organism)

Homo sapiens (Human)

Gene Names:

NXPH2

Tag info:

N-terminal 6xHis-Myc-tagged

Target Protein AA Sequence:

KEVVHATEGLDWEDKDAPGTLVGNVVHSRIISPLRLFVKQSPVPKPGPMAYADSMENFWDWLANITEIQEPLARTKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGLGNVSVSLVPPSKVVEFEVSPQSTLETKESKSFNCRIEYEKTDRAKKTALCNFDPSKICYQEQTQSHVSWLCSKPFKVICIYIAFYSVDYKLVQKVCPDYNYHSETPYLSSG

Expression Region:

23-264aa

Subcellular Location:

Secreted

Tissue Specificity:

Expressed in brain and kidney.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

31.5 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Neuroscience

Function:

May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.

Involvement in disease:

Relevance:

May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Neurexophilin family

Reference:

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. Wilson R.K.Nature 434:724-731(2005)