Alternative Name(s):

WAF-1/CIP1 stabilizing protein 39

Species: (Organism)

Homo sapiens (Human)

Gene Names:

FKBPL

Tag info:

N-terminal GST-tagged

Target Protein AA Sequence:

METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG

Expression Region:

1-349aa

Subcellular Location:

Tissue Specificity:

Ubiquitously expressed with higher levels in testis.

Protein Length:

Full Length

Pathway:

Mol. Weight:

65.2 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Cell Biology

Function:

May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.

Involvement in disease:

Relevance:

May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"A novel human stress response-related gene with a potential role in induced radioresistance." Robson T., Joiner M.C., Wilson G.D., McCullough W., Price M.E., Logan I., Jones H., McKeown S.R., Hirst D.G. Radiat. Res. 152:451-461(1999)