Alternative Name(s):

Odorant-binding protein IIa Short name:OBPIIa

Species: (Organism)

Homo sapiens (Human)

Gene Names:

OBP2A

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

LSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVSPVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYLQELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNTNLEALEEFKKLVQHKGLSEEDIFMPLQTGSCVLEH

Expression Region:

16-170aa

Subcellular Location:

Secreted

Tissue Specificity:

Strongly expressed in the nasal structures, salivary and lachrymal glands, and lung.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

33.8 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Neuroscience

Function:

Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids.

Involvement in disease:

Relevance:

Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Calycin superfamily, Lipocalin family

Reference:

"A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres."Lacazette E., Gachon A.-M., Pitiot G.Hum. Mol. Genet. 9:289-301(2000)