Alternative Name(s):

VP3; Apoptin

Species: (Organism)

Chicken anemia virus (isolate Germany Cuxhaven-1) (CAV)

Gene Names:

VP3

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

MNALQEDTPPGPSTVFRPPTSSRPLETPHCREIRIGIAGITITLSLCGCANARAPTLRSATADNSESTGFKNVPDLRTDQPKPPSKKRSCDPSEYRVSELKESLITTTPSRPRTAKRRIRL

Expression Region:

1-121aa

Subcellular Location:

Host nucleus

Tissue Specificity:

Protein Length:

Full Length

Pathway:

Mol. Weight:

29.3 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle.

Involvement in disease:

Relevance:

May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Gyrovirus apoptin family

Reference:

"Characterization of cloned chicken anemia virus DNA that contains all elements for the infectious replication cycle."Noteborn M.H.M., de Boer G.F., van Roozelaar D.J., Karreman C., Kranenburg O., Vos J.G., Jeurissen S.H.M., Hoeben R.C., Zantema A., Koch G., van Ormondt H., van der Eb A.J.J. Virol. 65:3131-3139(1991)