Alternative Name(s):

Alcohol dehydrogenase class-III Glutathione-dependent formaldehyde dehydrogenase Short name: FALDH Short name: FDH Short name: GSH-FDH S-(hydroxymethyl)glutathione dehydrogenase

Species: (Organism)

Arabidopsis thaliana (Mouse-ear cress)

Gene Names:

ADH2

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

ATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEGLFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATGVGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASGQEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKAFDLLHEGTCLRCVLDTSK

Expression Region:

2-379aa

Subcellular Location:

Cytoplasm

Tissue Specificity:

Ubiquitous.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

56.6 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Signal Transduction

Function:

Plays a central role in formaldehyde detoxification.

Involvement in disease:

Relevance:

Plays a central role in formaldehyde detoxification.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Zinc-containing alcohol dehydrogenase family, Class-III subfamily

Reference:

"Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis."Achkor H., Diaz M., Fernandez M.R., Biosca J.A., Pares X., Martinez M.C.Plant Physiol. 132:2248-2255(2003).