Alternative Name(s):

Acyltransferase which transfers an acyl group to the N-terminus of glutamine. Can use phenylacetyl-CoA as an acyl donor.

Species: (Organism)

Homo sapiens (Human)

Gene Names:

GLYATL1

Tag info:

N-terminal GST-tagged

Target Protein AA Sequence:

MILLNNSHKLLALYKSLARSIPESLKVYGSVYHINHGNPFNMEVLVDSWPEYQMVIIRPQKQEMTDDMDSYTNVYRMFSKEPQKSEEVLKNCEIVNWKQRLQIQGLQESLGEGIRVATFSKSVKVEHSRALLLVTEDILKLNASSKSKLGSWAETGHPDDEFESETPNFKYAQLDVSYSGLVNDNWKRGKNERSLHYIKRCIEDLPAACMLGPEGVPVSWVTMDPSCEVGMAYSMEKYRRTGNMARVMVRYMKYLRQKNIPFYISVLEENEDSRRFVGQFGFFEASCEWHQWTCYPQNLVPF

Expression Region:

1-302aa

Subcellular Location:

Tissue Specificity:

Expressed in liver and kidney and, at lower levels, in pancreas, testis, ovary and stomach.

Protein Length:

Full Length

Pathway:

Mol. Weight:

62.1 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Signal Transduction

Function:

Acyltransferase which transfers an acyl group to the N-terminus of glutamine. Can use phenylacetyl-CoA as an acyl donor.

Involvement in disease:

Relevance:

Acyl-CoA:glycine N-acyltransferase-like protein 1 Glutamine N-acyltransferase

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Glycine N-acyltransferase family

Reference:

"Molecular cloning and characterization of a novel human glycine-n-acyltransferase gene GLYATL1, which activates transcriptional activity of HSE pathway." Zhang H., Qu Y., Lang Q., Li J., Zhong Z., Xie F., Ye G., Wan B., Yu L. Int. J. Mol. Sci. 8:433-444(2008)