Alternative Name(s):

SELENOM; SELM; Selenoprotein M; SelM

Species: (Organism)

Homo sapiens (Human)

Gene Names:

SELM

Tag info:

Tag-Free

Target Protein AA Sequence:

ATAYRPDWNRLSGLTRARVETCGGSQLNRLKEVKAFVTQDIPFYHNLVMKHLPGADPELVLLGRRYEELERIPLSEMTREEINALVQELGFYRKAAPDAQVPPEYVWAPAKPPEETSDHADL

Expression Region:

24-145aa

Subcellular Location:

Cytoplasm, perinuclear region, Endoplasmic reticulum, Golgi apparatus

Tissue Specificity:

Widely expressed.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

13.9 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.

Involvement in disease:

Relevance:

May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Selenoprotein M/F family

Reference:

"Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element." Korotkov K.V., Novoselov S.V., Hatfield D.L., Gladyshev V.N. Mol. Cell. Biol. 22:1402-1411(2002)