Alternative Name(s):

FLJ11029 ; Homo sapiens proline rich 11 ; Proline rich protein 11 ; Proline-rich protein 11; PRR 11; Prr11; PRR11_HUMAN; transcription repressor of MHCII

Species: (Organism)

Homo sapiens (Human)

Gene Names:

PRR11

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

MPKFKQRRRKLKAKAERLFKKKEASHFQSKLITPPPPPPSPERVGISSIDISQSRSWLTSSWNFNFPNIRDAIKLWTNRVWSIYSWCQNCITQSLEVLKDTIFPSRICHRELYSVKQQFCILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLLTVKLKKTQSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGKSQMDLRKLLRKVDVERSPGGTPLTNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTLPLSTSSFDEQN

Expression Region:

1-360aa

Subcellular Location:

Cytoplasm, Nucleus

Tissue Specificity:

Ubiquitously expressed.

Protein Length:

Full Length

Pathway:

Mol. Weight:

56.1 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Cancer

Function:

Plays a critical role in cell cycle progression.

Involvement in disease:

Relevance:

Plays a critical role in cell cycle progression.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"PRR11 is a novel gene implicated in cell cycle progression and lung cancer."Ji Y., Xie M., Lan H., Zhang Y., Long Y., Weng H., Li D., Cai W., Zhu H., Niu Y., Yang Z., Zhang C., Song F., Bu Y.Int. J. Biochem. Cell Biol. 45:645-656(2013)