Alternative Name(s):

Orofacial clefting chromosomal breakpoint region candidate 1 protein

Species: (Organism)

Homo sapiens (Human)

Gene Names:

OFCC1

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

REKFQQKALKQTKQKKSKSAEFLMVKEDREATEGTGNPAFNMSSPDLSACQTAEKKVIRHDMPDRTLAAHQQKFRLPASAEPKGNEYGRNYFDPLMDEEINPRQCATEVSREDDDRIFYNRLTKLFDESRQGEPQDESGREETLNSEAPGSSNKSHEIHKEASEATTAHLEEFQRSQKTIILLGSSPLEQEIRSTSLHCMEDEMSHPWILLLKVTAVIRSRRYYREQRF

Expression Region:

3-231aa

Subcellular Location:

Tissue Specificity:

Protein Length:

Partial

Pathway:

Mol. Weight:

42.5 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Epigenetics and Nuclear Signaling

Function:

Involvement in disease:

A chromosomal aberration involving OFCC1 is found in patients with orofacial cleft.

Relevance:

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"Mapping of three translocation breakpoints associated with orofacial clefting within 6p24 and identification of new transcripts within the region."Davies S.J., Wise C., Venkatesh B., Mirza G., Jefferson A., Volpi E.V., Ragoussis J.Cytogenet. Genome Res. 105:47-53(2004)