Alternative Name(s):

RFP-like domain-containing protein trimless RING finger protein 36 Tripartite motif-containing protein 69

Species: (Organism)

Homo sapiens (Human)

Gene Names:

TRIM69

Tag info:

N-terminal GST-tagged

Target Protein AA Sequence:

MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ

Expression Region:

1-341aa

Subcellular Location:

Cytoplasm, Nucleus, Nucleus speckle

Tissue Specificity:

Protein Length:

Full Length of Isoform 2

Pathway:

Mol. Weight:

66.3 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Cell Biology

Function:

May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis.

Involvement in disease:

Relevance:

May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

TRIM/RBCC family

Reference:

"TRIMLESS defines a new class of RFP-like domain containing proteins." Merla G., Zanaria E., Cairo S., Meroni G., Reymond A. Submitted (SEP-2000)