Alternative Name(s):

Late envelope protein 13

Species: (Organism)

Homo sapiens (Human)

Gene Names:

LCE3A

Tag info:

N-terminal 10xHis-tagged

Target Protein AA Sequence:

MSCQQNQQQCQPPPKCPAKSPAQCLPPASSSCAPSSGGCGPSSERSCCLSHHRCRRSHRCRCQSSNSCDRGSGQQGGSSSCGHSSAGCC

Expression Region:

1-89aa

Subcellular Location:

Tissue Specificity:

Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.

Protein Length:

Full Length

Pathway:

Mol. Weight:

12.6 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Precursors of the cornified envelope of the stratum corneum.

Involvement in disease:

Relevance:

Precursors of the cornified envelope of the stratum corneum.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

LCE family

Reference:

"Late cornified envelope family in differentiating epithelia --response to calcium and ultraviolet irradiation." Jackson B., Tilli C.L., Hardman M., Avilion A., Macleod M., Ashcroft G., Byrne C. J. Invest. Dermatol. 124:1062-1070(2005)